People on the plane performed CPR on Carrie on Friday. Once the flight landed, paramedics rushed her to UCLA Medical Center where she has been ever since.
Her death has provoked an outpouring of emotion from heartbroken celebrities mourning the legendary actor’s death.
In a statement released on behalf of Fisher’s daughter Billie Lourd, a spokesman said: “It is with a very deep sadness that Billie Lourd confirms that her beloved mother Carrie Fisher passed away at 8.55 this morning.
“She was loved by the world and she will be missed profoundly. Our entire family thanks you for your thoughts and prayers.”
She gained sex symbol status in 1983’s “Return of the Jedi” when her Leia character wore a metallic gold bikini while enslaved by the diabolical Jabba the Hutt.
She returned last year in Disney’s reboot of the “Star Wars” franchise, “The Force Awakens”.
Star Trek hero William Shatner said: “I’m deeply saddened to learn of the death of Carrie Fisher. I will miss our banterings.
“A wonderful talent and light has been extinguished.”
Stephen Fry added: “She was the brightest, funniest, bravest, kindest, cleverest and sweetest person I ever knew. A crushing blow to lose.”
She was one of two children from the marriage.
Her brother Todd also followed in the family footsteps to carve out a career in the entertainment industry.
But her big break was landing the role of Princess Leia in the first instalment of the Star Wars Trilogy, Episode IV: A New Hope in 1977.
The movie became a global blockbuster and earned her the same fame as her mum Debbie Reynolds.
She was also a successful writer.